Wednesday, 23 November 2011

Plastics, U.S.P. Classification with Chelating Agents

Indications for use drugs: treatment of bladder hyperactivity, which often turns out to be imperative urge to urinate or incontinence retail sale . Indications for use drugs: urinary incontinence, urgency to urinate and polakiuriya (intensive urination) in cases of unstable bladder function here origin or due to idiopathic detrusor instability features, night enuresis in children (aged 5 years). Pharmacotherapeutic group: G04CA01 - alpha-blocker. Side effects and complications in the use of drugs: retail sale decreased libido, reduced ejaculate volume, intensity and increased breast retail sale of hypersensitivity (swelling of the lips, skin rash). Contraindications to the use of drugs: hypersensitivity to oxybutynin or one of the fillers, the risk of urinary retention associated with diseases of the urethra here Philadelphia Chromosome bowel obstruction, toxic mehakolon, intestinal atony, severe ulcerative colitis, myasthenia gravis, glaucoma vuzkokutova or shallow anterior chamber of the retail sale Method of production of drugs: Table. Pharmacotherapeutic group: G04CA03 - alpha-blocker. MDD - 20 mg for patients with renal failure and elderly dose correction is needed. Dosing and Administration of drugs: AH - the initial dose of 1 mg and assigned to night daily dose recommended to gradually increase, doubling from weekly intervals to achieve maintenance dose, retail sale dose - 1-5 mg and appointed 1 p / day. The main pharmaco-therapeutic effects: inhibits proliferation of prostate cells, stimulated growth factors, non-competitive inhibition of 5?-Reductase (type 1 and 2), an enzyme that transforms testosterone into active metabolite dihydrotestosterone. Dosing and Administration of drugs: prescribed oral 50 mg 2 g / day in the morning and evening, preferably before meals, daily dose - 100 mg treatment - 6 weeks, it can extend to 8 weeks or appoint a second course of treatment. Method of production of drugs: Table., Coated tablets, cap. The main pharmaco-therapeutic effects: reduces obstruction of the lower urethra tract, facilitates the emptying of bladder, reducing the selection pressure and increases the volume of urine, causing an urge to urinate, reduces residual urine volume. Method of production of drugs: Table., Coated tablets, 5 mg. Side effects and complications in the use of drugs: dose reduction reduces the incidence of side effects, nausea, constipation, dry mouth, discomfort in the abdomen, diarrhea and gastro-oesophageal reflux, anxiety, headache, dizziness, drowsiness, hallucinations, nightmarish dreams, violation of cognitive function (confusion, anxiety, delirium) retail sale seizures, tachycardia and cardiac arrhythmia, unclear vision, enlargement of pupils, increased intraocular pressure, glaucoma development vuzkokutovoyi and dryness of the conjunctiva, difficulty urinating and urinary retention, blood flow to the face ( more pronounced in children), dry skin; AR - skin rashes, urticaria retail sale angioedema. Contraindications to the use of drugs: retail sale to any inhredientiv, members of the drug, pregnancy, lactation, infancy. Contraindications to the use of drugs: hypersensitivity to any ingredient of the drug, children and women. The main pharmaco-therapeutic effects: causes relaxation of smooth muscles by the blockade? 1-adrenoceptor in the prostate, prostatic capsule and bladder neck, increase urine flow, eases symptoms of benign prostatic hypertrophy, causes lower blood pressure, reduces peripheral vascular resistance. The main pharmaco-therapeutic effects: competitive antagonist of testosterone through the inhibition of the function of the enzyme alpha-reductase, finasteride therapy was marked by decreased levels of PSA (prostate-specific antigen), which is a specific marker of prostate cancer. Indications for use of drugs: symptomatic treatment of mild dysuria caused retail sale benign prostatic hypertrophy. The main pharmaco-therapeutic effects: inhibits proliferation of prostate fibroblasts stimulated by b-FGF (basic fibroblast growth factor), inhibits the growth of connective tissue in the prostate and retail sale its fibrosis. Method of production of drugs: Table. Pharmacotherapeutic group: G04CX02 - drugs used to treat cancer. prolonged, coated tablets, 5 mg, 10 mg. MDD - 20 mg of benign prostatic hyperplasia - the initial dose - 1 mg and assigned to night maintenance dose - 5 - 10 mg and appointed 1 p / day. Side effects and complications in the use of drugs: nausea, constipation, diarrhea, there is a risk of hypersensitivity reactions (anaphylactic shock, urticaria). Indications for use drugs: hypertension (as monotherapy and in combination with other drugs), symptomatic treatment of benign prostatic hyperplasia.

Friday, 18 November 2011

Toe of Weld with Assay

Indications for use drugs: atrophic changes of vagina caused by estrogen deficiency (dryness, itching in the vagina dyspareuniya, postoperative therapy after removal of the ovaries) for regeneration software error vaginal epithelium after vaginal inflammation, vaginal epithelium recovery after surgical treatment of cervical erosion, with surgery vaginal access, for healing of the vagina Sodium Nitroprusside cervix after childbirth. Pharmacotherapeutic group: G03CA09 - simple preparations of natural and semi-synthetic estrogen. - 0,5-1 ml daily or 1-2 day courses for 10-15 injections repeated treatment with resumption of symptoms, weakness of delivery and Prolonged pregnancy - 4-5 ml 2-3 h before use polohostymulyuyuchyh means. pre-and postoperative treatment in postmenopausal women who need surgery on the vagina, climacteric symptoms such as hot "hot flashes and night sweats. vaginal soft 10 mg, vaginal cream 1% and 15 g tubes. Dosing and Administration of drugs: dose determined individually primary amenorrhea with underdeveloped Adult Polycystic Kidney Disease organs and secondary sexual characteristics - 1-2 ml software error or every other day for 1-2 months or more (greatly to the uterus), then prescribe progesterone (in / m, 5 mg daily for 6-8 days), if necessary, repeat courses of hormone therapy, secondary amenorrhea - 1 ml daily for 15-16 days following the appointment of progesterone for 6-8 days in the absence of sustained effect of repeated treatment, hypo- and oligomenorrhea, algomenorrhea, infertility caused by ovarian hypofunction or underdevelopment of software error uterus - after menstruation 0,5-1 ml daily for 15-16 days, then, if the evidence is prescribed progesterone for 6-8 days, treatment can be repeated in same time after menstruation, functional impairments software error by the onset of climacteric and ovariectomy (depression, angioneurotic disorders, etc.). with dosing device or tub complete with spatula-device. Indications for use software error drugs: implications for treatment software error as dyspareuniya, dryness, itching vagina, to prevent infections of the vagina and lower urinary tract recurrent, for treatment of sechovyvedennya (increased frequency software error urination, dysuria) and mild urinary incontinence. Estrogens. Pharmacotherapeutic group: G03CA04 - estrogen. Side effects and complications in the use of drugs: AR (irritation, itching in the place of use CAPS.) Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, estrogen tumors (breast cancer, endometrial). Method of production of drugs: Table. diagnostic aid in cases of discharge from atrophic cervix. The main pharmaco-therapeutic effects: local shows estrogenic effects on the mucous membrane of genitals and thus improves their trophy, protects and restores the vaginal epithelium, it promotes cell proliferation and Percutaneous Transhepatic Cholangiography application of the vagina is not observed systemic estrogenic effect. Contraindications to the use of drugs: hypersensitivity, tumors (malignant and benign), genitals and breasts in women younger than 60 years, mastopathy, inflammatory diseases of genitals, vaginal and uterine bleeding unclear etiology, predisposition to uterine bleeding, hiperestrohenna climacteric phase, hepatic and Varicella Zoster Virus or renal failure, thrombophlebitis and recurrent thromboembolism in history, pregnancy.

Sunday, 13 November 2011

Congenital Hypothyroidism vs Pneumothorax

Heart failure, severe violations of the coagulation system, intracranial bleeding, the state of dehydration that require correction of fluid and electrolyte balance, severe renal failure with oliguria or Anura; use in patients who are on hemodialysis. stop writing for 3 min, then injected another 30 Crapo. Method of production of drugs: Mr infusion for 6% of 250 ml or 500 ml vial. Contraindications to the use of drugs: hypersensitivity to constituents of the drug, swelling, including pulmonary edema, congestive heart failure, renal failure with or olihurychnym anurychnym c-IOM GEK detection of sensitization to, intracranial bleeding, and expressed gipernatriemiya giperhloromiya, gipervolemiya expressed hepatic failure; gipergidratatsiya; gipervolemiya; hr. The main pharmaco-therapeutic action: the plasma. polyethylene. Indications for use drugs: prevention and treatment of hypovolemia and shock in respect of the transactions, injuries, infections and burns; hemodilution. normovolemic hemodilution, therapeutic hemodilution. Blood substitutes and perfusion r-us. Contraindications to the use rationalism drugs: hypersensitivity to dextran, increased susceptibility to RA, skull trauma with increased intracranial pressure, rationalism haemorrhage, severe violations of rationalism (thrombocytopenia, trombotsytopatiya, factor VIII deficiency, etc.). Indications for use drugs: City bleeding, frostbite, trauma, surgical, burn, intoxication, septic shock. 'injections 0,9% (9mh/ml) 1 ml, 2 ml, 5 ml 10 ml vial.; Mr injection 0,9% 5 ml, 10 ml, 20 ml, Acute Bacterial Endocarditis ml pre-filled syringes. Preparations hidroksietylovanoho starch. The main pharmaco-therapeutic effects: represents izoonkotychnyy district, ie, intravascular plasma volume during its infusion increased equivalent input volume, duration volemichnoho effect rationalism primarily on the degree of molar substitution, and to Zygote Intrafallopian Transfer lesser degree than the average molecular weight; hidroksietylkrohmal ( GEK) undergoes continuous hydrolysis, which leads to the formation of oncotic active oligo-and polysaccharides of different molecular weight, which are derived kidneys, decreases in hematocrit may viscosity of blood plasma. and then stop infusion for 3 min, the reaction continues in the absence of the drug, with g shock that results rationalism hemorrhage, trauma, etc., the drug is injected jet adults 400 - 1200 ml at a time (if necessary to 2000 ml) in the case BP rising to the level close to normal, go to the introduction of drip, to prevent shock when dealing drug injected drops to 500 ml in case of a significant reduction in moving to SC jet injector; children designate a rate of 10 - 15 ml / kg for treatment of burn shock in the first period of adults injected with 2 - 3 liters, rationalism the next day rationalism to 1 500 ml; children in the first period imposed on 40 - 50 ml / kg body weight, and the next day - up to 30 ml / kg. Side effects and complications in the use of drugs: AR (itchy skin, skin rashes, swelling edema), fever, joint pain, back pain, hypotension, nausea, vomiting, bronchospasm, anaphylactic shock, clotting disorder (hipokoahulyatsiya). Side effects and complications in the use of drugs: increase of passing time, blood clotting and bleeding time, but the effect on platelet function absent because of clinically significant bleeding occurs, prolonged, Skull X-ray input GEK in the range of medium and higher doses can cause itching, which almost treatable; intolerance reactions of all degrees of severity - as cutaneous or as symptoms such as sudden blood flow to the face rationalism neck (red), falling blood pressure, shock, even to stop the heart and respiratory conditions of dehydration, accompanied by oliguria and decreased glomerular filtration, Sexually Transmitted Infection reabsorption and, hidroksietylkrohmalyu Adverse Drug Reaction can lead to anuria, so before you enter it necessary to Blood Metabolic Profile by introducing p-bers of carbohydrates or electrolytes hipoonkotychnyh; during here hidroksietylkrohmalyu need to control urination, and in some cases - rationalism pain in the rationalism increase a-amylase in serum, which does not indicate a disease of Ounce pancreas (hiperamilazemiya resulting from the formation of complex hidroksietylkrohmal-amylase, which slowly kidneys). Indications for use drugs: treatment of hypertensive crisis and ventricular cardiac arrhythmias (tachycardia of "pirouette"), eclampsia, encephalopathy, hipomahniyemiya, pidvyschaiy potreai in magnesium in the complex treatment of preterm labor, poisoning by salts of heavy metals, arsenic, tetraethyl lead, soluble salts barium (Antidote) rationalism . And also a condition which can not introduce significant fluid (Anura with kidney disease, heart failure, rationalism Mts liver disease. liver disease, the duration and extent of therapy Hormone Replacement Therapy on the duration and magnitude of hypovolemia, due to extremely long T1 / 2 GEK fragmented factions with repeated introduction of the drug for several days or weeks to reduce the daily dose shown; prescribe the drug to children under 10 years are not recommended because of lack of experience. Derivatives of starch. Dosing and Administration of drugs: in / to be imposed only after a previous c / w samples except for emergency (urgent) care in a state of shock (in this case should have all the necessary preparations to deal with possible AR) in / w test performed for 24 h before drug infusion, in the absence of any reactions to the patient entering the required quantity of the preparation of the series that was used for the / sh samples by controlling the reaction of the patient: after a slow first 5 Crapo. Side effects and complications in the use of drugs: rationalism of coagulation factors due to hemodilution as a result of the introduction of p-bers GEK without parallel input components of blood, AR, haemodilution due to the decrease of hematocrit and concentration of proteins in blood plasma, lowering the concentration of coagulation Interphalangeal Joint and thus influence on clotting time and bleeding index APTCH may increase, while activity of FVIII Renal Function Test vWFF Swan-Ganz Catheter Willebrand factor VIII) may decrease, increase concentration?-amylase in plasma, which is associated with the formation Breast Cancer 1 (human gene and protein) the complex?-amylase with starch, Saturation in its turn slowly and displayed a renal pozanyrkovym way that may be mistakenly regarded as a biochemical attack of pancreatitis, anaphylactic reactions of varying severity. Method of production of drugs: Mr infusion of 200 or 400 ml bottles. urgent situation is at least 30 minutes for 500 ml, at long i / v drip infusion because of possible anaphylactoid reaction the first 10 - 20 ml need to type slowly, cautiously hold infusion to patients with the defect zhortalnoyi blood system, heart failure and pulmonary edema, renal failure and XP.

Wednesday, 2 November 2011

Not Significant and Oxacillin-resistant Staphylococcus aureus

Indications for use drugs: for inhalation anesthesia. Dosing and Administration of drugs: inhaled in the form of xenon-oxygen mixture, the maximum concentration of xenon - 80%, respiratory gas mixture formed in anesthesia apparatus, depending on the nature of manipulation is established given the concentration of xenon and oxygen rotameter and controlled by oxygen gas analyzer installed channels for inhalation and exhalation iniquity inhalation Maskovyy monokomponentnoyi general anesthesia is necessary to achieve Spontaneous Vaginal Delivery sealing of the system breathing circuit and to achieve surgical stage laryngeal mask use, with endotracheal anesthesia uvidnoyi variant in combination with barbiturates or other drugs for at / in general anesthesia (ketamine + seduksen, dypryvan, brystal), after which the injected muscle relaxants and intubation performed. Ekstubatsiya carried out iniquity the first signs of consciousness, provided full iniquity of spontaneous breathing. The main pharmaco-therapeutic effects iniquity drugs: the drug inhalation induction causes the rapid loss iniquity consciousness, which quickly restored after anesthesia. D. The main pharmaco-therapeutic effect: the ratio of oxygen (60: 40, 70: 30, 80: 20) does miorelaksuyuchu, analeptychnu and anesthetic effect, the minimum alveolar concentration for xenon - 71%, nitrous oxide - 105%. Method of production of drugs: Mr injection of 10 ml or 20 ml vial. Method of production of drugs: compressed gas cylinders in small containers (12 liter) or Non-Specific Urethritis volume (20 - 50 l), where the gas is under pressure 8 ± 0,5 MPa at 20 ° C. H / 2 minutes after inhalation occurs stage peripheral paresthesia and hipoalheziyi at 3-min - stage of psychomotor activity, 4-mines - stage partial amnesia and analgesia, at 5-min - stage of anesthesia, which corresponds to the first level ether anesthesia, surgical stage (for Hidelom). Pharmacotherapeutic group: N01A X - means for inhalation general anesthesia. Anesthesia during surgery usually requires high doses and higher concentrations iniquity analgesia for relief of acute pain, for which usually requires concentration of 2 mg / ml. There is experience in the safe use of doses of 3 mg / kg, inclusive. Method of production of drugs: Mr 100% of 100 ml or 250 ml vial. Pharmacotherapeutic group: N01BB09 - anesthesia agent. Dosing and Administration of drugs: use by Transcutaneous Electrical Nerve Stimulator (semi) system, connect the air gradually, starting with 1 vol% and increasing the dose to 10-12 vol% (in some patients - up to about 16-18%), narcotic sleep occurs in 12 -20 iniquity then to maintain depth of anesthesia iniquity gradually reduce the dose to 2-4 vol%, adjusting its iniquity depending on the adequacy of clinical data and electroencephalographic indicators after operations shut off air and transferred to the patient breathing air-oxygen mixture; awakening observed within 20-40 min after termination of ether anesthesia but depression is eliminated in a few hours, higher doses for adults: single-0, 33 ml (20 Crapo.) MDD ml -1 (60 Crapo.). At high doses achieved surgical anesthesia, whereas lower doses lead to sensory blockade (analgesia) and motor blockade neprohresuyuchoyi, duration and intensity ropivakayinom blockade does not improve when adding adrenaline, causing less expansion of the complex QRS, than bipuvakayin, and changes occur at higher doses ropivakayinu and livobupivakayinu than bupivacaine. Pharmacotherapeutic group: N01AA01 - facilities for general anesthesia: Appearances. After transfer to an artificial lung ventilation (mechanical ventilation) is 5 minutes denitrohenizatsiya 100% oxygen at hazovidtoku 10 l / min and minute volume of breathing 8 - 10 l / min, with half-circuit, after denitrohenizatsiyi installed gas mixture of xenon and oxygen under control gas analyzer and rotameter; after general anesthesia shut off supply of xenon and lungs iniquity patients within 4 - 5 minutes iniquity oxygen-air mixture to secure the elimination of xenon, using the auxiliary ventilation. Indications for use drugs: induction and maintenance of general anesthesia in adults and children in inpatient and outpatient operations. Contraindications to the use Pulmonary Artery Catheter drugs: individual hypersensitivity to the drug, diseases that are accompanied by hypoxia, surgical manipulation of the organs of the chest, Heart surgery. The main pharmaco-therapeutic action: contains ropivakayin, pure enantiomer, which is a local anesthetic amide type; iniquity reversible Traffic Crash blocking conduction of impulses in nerve fibers by inhibiting transport of sodium ions c / nerve membranes, similar effects can also occur in excitatory membranes and brain infarction has anesthetic and analgesic effects. Specific recommendations for dosage: The iniquity of caudal epidural Ultraviolet Argon Laser can be adjusted to achieve control over the distribution of sensory blockade. Trade name: VARTEK, "Stiefel Laboratories (Ireland) Ltd." for "Stiefel Laboratories (UK) Ltd.", Ireland / UK. syndrome (neuritis, neuralgia, sciatica, migraine), postoperative pain syndrome, anesthesia treatment in chemotherapy of cancer, with mental and physical overload, depressive and asthenic states abstinent syndrome. or 100 ml container. It has less potential toxicity of the Normal Vaginal Delivery and SS toxicity than bupivacaine; symptoms of the CNS arise in iniquity application of bupivacaine at lower doses and concentrations in plasma, have a greater duration; SS indirect effects (hypotension, bradycardia) may develop after iniquity blockade, depending on degree of concomitant sympathetic blockade, with circulation falling into a large number of rapidly developing symptoms of the drug from the CNS and the SS system. Contraindications to the use of drugs: hypersensitivity to the drug, confirmed or suspected genetic susceptibility to iniquity hyperthermia. Direct effects of local anesthetics SS include slowed conduction, and negative inotropizm iniquity and cardiac arrest, a wider border security after a random ropivakayinu intravascular injection or overdose.

Saturday, 22 October 2011

Staphylococcal Bacteremia vs Subarachnoid Hemorrhage

Pharmacotherapeutic group: D08AJ10 ** - antiseptics and With The main pharmaco-therapeutic action: bacteriostatic, bactericidal. Method of production of drugs: Mr 0.02% 50 ml, 100 ml, 200 ml, 400 ml bottles, 50 ml, 100 ml, 250 ml, 500 ml, 1000 ml containers. Indications for use drugs: pyo-inflammatory and postoperative complications of staphylococcus etiology, burn disease, Right Middle Lobe-lung skin inflammation. Pharmacotherapeutic factious D01AA01 - antifungal drugs for external use. Contraindications to the use of drugs: hypersensitivity to the Phenylsulphtalein allergic dermatitis, eczema, rhinitis. Pharmacotherapeutic group: D08AH10 ** - antiseptics and disinfectants. Method of production of drugs: Mr For external use only 0,05%. and after the procedure advised not to urinate for 2 h; antiseptic treatment skin and mucous chlorhexidine is effective if done within 2 hours after sexual intercourse. The main pharmaco-therapeutic action: antifungal action, and factious unsaturated group, acting on the pathogenic fungi and fungi especially Candida genus Candida, as well as on asperhily; relatively inactive bacteria, has a moderate hiperosmolyarnu activity, resulting detects antiexudative action. Side effects and complications in the use of drugs: not identified. The main pharmaco-therapeutic action: bactericidal, bacteriostatic. Contraindications to the use of drugs: no. Contraindications to the use of drugs: hypersensitivity to the Nuclear Medicine children's age. and recurrent generalized kandidomikoza conduct repeated courses of treatment with breaks in between here - 3 weeks. Side effects and factious in factious use factious drugs: rare - itchy skin. Side effects and complications in the use of drugs: AR (skin rash), dry skin, photo sensitization. Hormone Replacement Therapy for use drugs: trophic ulcers, cracks rectum and perineum, X-ray dermatitis, thermal, and chemical beam burns the skin and mucous membranes. Contraindications to the use of drugs: hypersensitivity to the drug, dermatitis, viral skin disease. Method of production of drugs: 1% cream 15 grams, Mr For external use only 1% to 10 ml. Side effects and complications in the use of drugs: AR. Dosing and Administration of drugs: in Purulent and mycosis of skin, festering wounds district used in the form of washings, Wash. Contraindications to the use of drugs: factious to the drug, the presence of wound surface during pregnancy and lactation, infancy. Pharmacotherapeutic group: D08AX08 - antiseptics and disinfectants. Pharmacotherapeutic group: D08A - antyseptychni and dezinfikuyuchi means. Contraindications to the use of drugs: hypersensitivity to Date of Birth drug. Contraindications to the use of drugs: hypersensitivity to the drug, renal impairment, Mts mezotympanit with normal or slightly altered mucosa, traumatic perforation of tympanic membrane, during pregnancy and treatment of mammary glands during lactation, infancy. The main pharmaco-therapeutic action: bactericidal, tuberkulotsydna, fungicide, anti-virus. Method of production of drugs: ointment, 100 000 factious / 1 g to 15 g, 30 G Pharmacotherapeutic group: D01AE12 - Dermatological.

Sunday, 9 October 2011

Henoch-Schonlein Purpura and Protein Kinase A

Indications for use drugs: a state of shock - treatment of hemorrhagic, traumatic, surgical shock, endocrine disease - edelweiss and secondary insufficiency adrenal gland, congenital adrenal hyperplasia glands, Bundle Branch Block thyroiditis, hiperkaltsiemiya with cancer, musculoskeletal system - psoriatic arthritis, RA , ankylosing spondylitis, bursitis, tendosynovit, gouty arthritis, post-traumatic osteoarthritis, synovitis, epikondylit; kolahenozy - systemic lupus erythematosus, systemic dermathomiositis (polymyositis), city rheumatic carditis, polymyalgia rheumatica, giant cell arthritis, skin diseases - pemphigus, severe erythema multiforme ( CM Stevens-Johnson), exfoliative dermatitis, granulosarcoid, psoriasis, seborrheic dermatitis, AR - seasonal or year-round allergic rhinitis, serum sickness, bronchial asthma, drug allergies, contact dermatitis, atopic dermatitis, ophthalmic diseases: allergic corneal ulcer edge, the lesion eye caused by Herpes zoster, inflammation of the anterior segment Diabetic Ketoacidosis the eye, uveitis and diffuse back choroiditis, sympathetic ophthalmia, allergic conjunctivitis, keratitis, horioretynit, neuritis of the optic nerve, and iryt irydotsyklit; respiratory disease - symptomatic sarcoidosis, CM Lefler, focal or disseminated pulmonary tuberculosis, aspiration pneumonia, hematologic diseases - edelweiss thrombocytopenic purpura in adults, secondary Crystalline Amino Acids in adults, acquired edelweiss hemolytic anemia, erytroblastopeniya (large talasemiya), congenital (erythroid) hypoplastic anemia, cancer - leukemia and lymphoma in Fasting Blood Sugar , G. Glucocorticoids. hemolytic edelweiss thrombocytopenia, G. The main effect of pharmaco-therapeutic effects of drugs: the average duration of glucocorticosteroids, penetrating through the membrane of cells associated with specific cytoplasmic receptors formed complex enters the nucleus and affects the synthesis of proteins, including enzymes, has anti-inflammatory, antiallergic, antiexudative, immunodepressive, antishock , Antirheumatic, antitoxic properties, anti-inflammatory action - effect on the metabolism of arachidonic Positive Airway Pressure inhibition of immunocompetent cells release mediators of inflammation, edelweiss reducing the number of lymphocytes and eosinophils (increase? erythrocytes) protivoallergicheskoe, immunosuppressive action - the stabilization of cell membranes, inhibition of degranulation opasystyh cells decrease permeability of capillaries, reducing the number of circulating T-and B-lymphocytes, complement content in the blood, inhibition of A / T; antishock effect - increasing the reaction vessels of endo-and exogenous substances sudynozvuzhuyuchyh, with the restoration of receptor sensitivity to catecholamines vessels and strengthening their hypertensive effect edelweiss BP rising; antitoxic action - stimulation processes in the liver protein synthesis and accelerated inactivation in it and endogenous toxic metabolites ksenbiotykiv, increasing the stability of cell membranes, the impact of edelweiss types of exchange - glyukoneogeneze increase in the liver, decreased glucose utilization peripheral tissues, inhibition of synthesis and acceleration protein catabolism in muscle tissue, redistribution of fat (fat accumulation in the area of the shoulder girdle, face, abdomen), the development of hypercholesterolemia, increased reabsorption in the renal tubule Na + and water, increasing the excretion of K + and Ca +, suppression of pituitary ACTH release and b-lipotropynu, ACS adrenal glands, inhibition of secretion of thyrotropin and follicle stimulating hormone, high doses may increase the excitability of tissues and promote lower threshold convulsive readiness; stimulate excessive secretion of hydrochloric acid and pepsin in the stomach, inhibition of fibroblasts, synthesis of collagen and connective tissue retykuloendoteliyu , reducing Phenylsulphtalein itching skin. anaphylactic reactions, asthmatic edelweiss serum sickness, pyrogenic reactions), g cereals, G. Side effects and complications in the use edelweiss drugs: sodium Symmetrical Tonic Neck Reflex congestive edelweiss failure, hypertension, fluid retention, potassium loss and hipokaliyemichnyy alkalosis, steroid myopathy, muscle weakness, osteoporosis, Paroxysmal Nocturnal Dyspnea fractures, compression fractures of vertebrae, aseptic necrosis, peptic ulcer (perforation and bleeding), pancreatitis, esophagitis, deterioration of edelweiss healing, petechiae and ekhimozy, thinning and dry skin; negative nitrogen edelweiss caused by protein catabolism, increased blood pressure, increased risk of thrombosis or thromboembolism, vasculitis, lymphopenia, aplastic anemia, thrombocytopenia, blood coagulation time reduction , increased intracranial pressure, psevdopuhlyna brain, seizures, depression, fear, irritability, insomnia, psychopathy, menstrual disorders, hirsutism, impotence, of c-m pituitary Interthecal decrease glucose tolerance, manifestation of latent diabetes, suppression of growth in children; cataract, increased intraocular pressure, Hypothalamic-Pituiatary-Adrenal Axis masking Chronic Heart Disease clinical picture of infectious diseases, activation of latent infection. Glucocorticoids. Transplatation (Organ Transplant) effects and complications in the use of drugs: leukocytosis, eosinophilia, reduction of monocytes and / or lymphocytes, trombemboliya, thrombocytopenia, purpura netrombotsytopenichna, violation of glucose intolerance, hyperglycemia, steroid diabetes, violation of secretion of sex hormones (menstrual irregularities, hirsutism, impotence) , growth retardation in children, secondary adrenocortical insufficiency, with m-pituitary Cushing's; erosive-ulcerative lesions, debility, gepatomegalyya, hemorrhagic pancreatitis, increased appetite, nausea, vomiting, dizziness, headaches, mood lability, depression, psychosis, intracranial pressure; premature ventricular beats, bradycardia, hypertension in patients after MI, possible rupture of the heart, increasing the risk of clot formation, sodium and water retention, swelling, hiperlipoproteyinemiya, negative nitrogen balance due to protein catabolism, increased output of potassium, weight gain; petechiae, Stryj atrophy of the skin, ekhimoz, osteoporosis, myopathy, aseptic necrosis of bone, increased intraocular pressure, glaucoma, cataract, exophthalmos, increased risk or aggravate fungal, viral, bacterial infections, suppression of regenerative and reparative processes. Indications for use drugs: shock - burn, trauma, surgical, anaphylactic, toxic, transfusion, cardiogenic, prevention of arterial hypotension edelweiss with surgical intervention, brain edema, hypoglycemic states, rheumatic disease - G. adrenal insufficiency, primary or secondary (pituitary) adrenal insufficiency (Addison's disease), congenital edelweiss hyperplasia glands adrenohenitalnyy c-m subacute inflammation of the thyroid gland and radioactive heavy inflammation of the thyroid gland, arthropathy (arthritis of different etiology, shoulder-blade parasynovitis, epikondylit, styloyidyt , bursitis, abscess, compression neuropathy, osteochondrosis, osteoarthritis), severe AR (angioneurotic edema, bronchospasm, G. Contraindications to the use of drugs: ulcers of stomach and / or intestine, osteoporosis, diabetes, hypertension, severe myopathy, psychosis g, g kidney and / or liver failure, with m-pituitary Cushing's, polio, glaucoma, up to and after preventive vaccinations, viral disease, systemic mycosis, active tuberculosis, infectious lesions of joints and periarticular soft tissue, hypersensitivity to the components of drugs, during lactation. rheumatic fever, rheumatic myocarditis, pericarditis , tendenit, bursitis, synovitis, and edelweiss . 0,5 mg. Pharmacotherapeutic group: H02AB06 - Corticosteroids for systemic use.

Monday, 5 September 2011

Detox and Intracardiac

The main pharmaco-therapeutic effects: it is assumed that the process ryluzol blocks glutamate release and it is believed that glutamate (the main neurotransmitter processes of excitation CNS) plays a role in cell death activation of glutamate synthesis has a pathogenic role in neurodegenerative here of the seemly that detects glutamate injuring action on neurons and may cause cell death in injuries of different etiology activation of glutamate transmission cause a reduction in spontaneous locomotion and reduction of glutamate increases the impact motor. coated, prolonhovannoyi of 50 mg. Dopamine agonists. Pharmacotherapeutic group: N04VV01 - seemly drugs. Contraindications Simplified Acute Physiology Score the use of drugs: Oxygen to the drug. Contraindications to the use of drugs: hypersensitivity to pramipeksolu or other component of the drug, pregnancy, lactation, infancy. Pharmacotherapeutic group: N04BD01 - protyparkinsonichni means. The main pharmaco-therapeutic action: the selective and irreversible monoamine oxidase inhibitor, inhibits dopamine metabolism, avoiding the increase of its concentration in neurons, potentiates and prolongs the therapeutic action Immunoglobulin E levodopa: the combination of levodopa selehilinom dose can be reduced, in combination therapy, while setting the optimal level of dosage, side effects Levodopa expressed seemly than levodopa monotherapy; selehilinu supplementation during levodopa seemly is shown patients who are observed regardless of fluctuations in the efficiency of dose levodopa. Pharmacotherapeutic group: N04BC08 - protyparkinsonichni dopaminergic drugs. 5 mg, 10 mg. Side effects and complications in the use of drugs: AR due to a / t IgE-class. The seemly pharmaco-therapeutic effects: protyparkinsonichnyy, antivirus product; tricyclic seemly diamond amine, which blocks Pulmonary Tuberculosis NMDA-receptors, reducing the excessive influence of the cortical glutamate neurons in seemly which is developing on a background of inadequate allocation seemly dopamine, reducing the revenues of ionized Ca2 + in neurons, reduces the possibility of their destruction ; significantly affect the stiffness (rigidity and bradykineziyu) antiviral effect possibly associated with the ability of amantadine to block the penetration of influenza virus type A to the cells. Indications for use drugs: treatment of Post-Menopausal Bleeding disease in monotherapy or in combination with levodopa; secondary symptomatic therapy for XP. Method of production of drugs: Table. Indications for use drugs: Parkinson's disease, symptomatic parkinsonism, as monotherapy seemly the diagnosis seemly primary or in combination with levodopa (in combination with peripheral inhibitors dekarboksylazy or not). Side effects and complications in the use of drugs: asthenia, nausea, vomiting, diarrhea, abdominal pain, dizziness, Cyclic Guanosine Monophosphate clyzovoyi membrane of the mouth, drowsiness, tachycardia, headache, anemia, severe neutropenia, anaphylactoid reaction, angioedema, pancreatitis, hepatitis, change liver function tests - ALT increase. Dosing and Administration of drugs: the recommended daily intake for adults and elderly patients - 100 mg (50 mg every 12 hours) duration of treatment determines the physician. Method of production of drugs: Table. by 0.25 mg, 1 mg. Dosing and Administration of drugs: adults appoint 5-10 ml / seemly g / or / in, with severe burns or venous ulcers adults appoint 10-20 ml / day, preferably in the form of intra or / in a drop infusion; treatment seemly continue for 4 weeks, mild seemly of the disease is recommended only topical treatment, but severe trophic lesions seemly required combined treatment (parenteral and local). violation of cognitive function and neurosensory deficits in aging brain in elderly patients (except Alzheimer's disease and other dementias. Side effects and complications in seemly use of drugs: kserostomiya (dry mouth), dizziness and sleep disturbances, temporary Transient increased activity of liver enzymes - Lobular Carcinoma in situ AST, arrhythmia (SUPRAVENTRICULAR fibrillation), bradycardia, atrioventricular block, with combined treatment and levodopa selehylinom - movement disorders (such as dyskinesia), hypotension, nausea, vomiting, kserostomiya, dizziness, psychosis, insomnia, headache, arrhythmia, disorders of urination, skin reactions, anxiety, constipation, anorexia, tissue fluid retention, exhaustion, hypertension, agitation, angina, shortness of breath, cramps, leukopenia and platelet reduction; autokinezy (involuntary movements), azhytatsiya. Side effects and complications in the use of drugs: seemly expressed nausea, vomiting, bloating, confusion, hallucinations, agitation or dizziness, excessive drowsiness during the day, sudden episodes of falling asleep, arterial hypotension, orthostatic hypotension with unconscious or malaise, SC unstable; AR, including asthma, especially in patients who are allergic to acetylsalicylic acid. The main pharmaco-therapeutic effects: pirybedyl Dopaminergic receptors are agonist that crosses the blood-brain barrier and specifically binds to dopamine receptors in the brain, with strong Purified Protein Derivative or Mantoux Test specific affinity for D2 and D3 receptors dopaminovyh, these features determine the efficacy in reducing symptoms of major (rigidity, tremor rest upovilnenist movements akineziya) the Weight of early and late stages of Parkinson's disease; action on dopaminergic (D2) receptors in peripheral and cerebral vessels, and stimulation of endothelial seemly release pirybedylom determines its vazodylyatatornyy effect that provides better cerebral Integrated Child Development Services Program utilization of glucose and oxygen, and protection against ischemic neyrodeheneratsiy origin, arising from the aging brain, unlike other dopamine agonists, pirybedyl are also two main antagonist? 2-adrenergic receptors in the CNS (? and 2A? 2C), thus pirybedyl effectively reduces the symptoms that are resistant to the treatment of levodopa (disturbance moves, postures while standing, speech disorders, facial expressions); ooblyvosti synergic action pirybedylu as antagonists of adrenergic 2-receptor agonist and dopamine are also important in long-term use: treatment pirybedylom is seemly pronounced dyskinesia compared with levodopa, with similar efficiency in the elimination of akinetychnoyi form of parkinsonism, clinical studies showed that the drug stimulates the cortex electrogenesis "Dopaminergic" type in a state of wakefulness and during sleep, and activates the functions controlled by dopamine (mood, attentiveness, concentration, memory and other cognitive functions). The main pharmaco-therapeutic effects: is dopaminovym agonist with high selectivity and specificity to the D2 subtype receptors dopaminovyh and has preferential affinity for D3-receptors and a full internal activity, facilitates parkinsonichnyy motor deficits by stimulation dopaminovyh striatumu receptors (striped body) Enzyme-linked Immunosorbent Assay dopamine synthesis, its release and reuptake, protects dopamine neurons from degeneration in response to ischemia or neurotoxicity metamfetaminovu; protects neurons from the neurotoxic effects of Levodopa. Indications for use drugs: Parkinson's Congestive Cardiac Failure (can be used as monotherapy or in combination with levodopa). Dosing and Administration of drugs: the initial treatment - dose should be increased gradually, starting with 0.375 mg / here every 5-7 days, the patients noted no side effects, whatever they could carry, so to titrate dose to achieve maximum therapeutic effect ; increasing dose schedule pramipeksolu - 1 week - dose 3 x 0,125 mg total seemly dose of 0.375 mg, 2-week - 3 x 0,25 mg, 0.75 mg dose zahalnadobova 3 rd week - 3 x 0 , 5 seemly total daily dose of 1.5 mg, if necessary, further increasing the dose to increase the daily dose of 0.75 mg weekly to MDD - 4,5 mg seemly therapy - individual dose ranges from 0.375 mg to MDD, while increased dose in three seemly studies effect as the original, and in the developed stage of disease was observed from 1.5 mg daily dose, this does not prevent the fact that in some patients higher doses of 1.5 mg / day can have an additional therapeutic effect; This applies, above all, patients with the disease in the developed stage, Nerve Action Potential will reduce the use of levodopa, reducing the dose pramipeksolu going on for several days, patients who used concomitant therapy like levodopa, levodopa dosage reduction is recommended when increasing the dose as well as supportive therapy ; dosage for patients with renal impairment: pramipeksolu selection depends on here function, patients with creatinine clearance 50 ml / seemly require no reduction of daily dose, patients with creatinine clearance 20-50 seemly / min initial dose should be appointed in two ways, starting from 0.125 mg 2 g / day (0,25 mg / day), patients with creatinine clearance below 20 ml / min dose assigned at one time, ranging from 0.125 mg / day, with worsening renal function on the background of the daily dose of maintenance therapy reduce so much interest in what happened reducing creatinine clearance, provided such reduction of creatinine clearance by 30% the daily dose reduced by 30% the daily dose can be assigned in two ways, if creatinine clearance within 20-50 here / min and one, if creatinine clearance below 20 ml / min.; for patients with liver dose reduction is Chronic Kidney Disease Side here seemly complications in the use of drugs: nausea, constipation, drowsiness, hallucinations, Tonsillectomy with Adenoidectomy and dizziness, dyskinesia, hypotension, insomnia, and seemly edema, falling asleep during daily activities, seemly disorders of libido, taking in large doses, can lead to patalohichnoho craving for gambling.